Expression of tocopherol-associated protein in mast cells.
نویسندگان
چکیده
Tocopherol-associated protein (TAP) was expressed in mouse mast cells. TAP was predominantly localized in the cytoplasm, and the subcellular localization was not changed by alpha-tocopherol. The results suggest that the physiological role of TAP in mast cells is not regulation of tocopherol function but an as-yet-unidentified activity.
منابع مشابه
The Effect of Smoking on Mast Cells Density and Angiogenesis in Chronic Periodontitis
Background and objective:Gingival bleeding reduction in smokers has been associated with decreased blood vessel density. The mechanism of suppressive effect of cigarette smoking on blood vessel density is not precisely defined. The aim of this study was to evaluate the impact of smoking on angiogenesis by assessing mast cells density and VEGF expression in chronic peri...
متن کاملImmunopotentiotor Effect of α-Tocopherol on Cytokine Expression in the Lymphocytes in the Elderly People
Background: Aging is associated with attenuation of immune responses. Studies show that old people are vulnerable to infectious diseases such as influenza. α-Tocopherol as an immunomodulator affects immune responses. In the present study, the effect of α-tocopherol, on lymphocyte responses i.e. interferon-gamma (IFN-γ), Tumor Necrosis Factor-alpha (TNF-α), and nuclear factor-κB (NF-κB) in elde...
متن کاملMAST CELLS IN THE TYMPANIC PART OF THE FACIAL NERVE IN CHRONIC OTITIS MEDIA WITHOUT ASSOCIATED FACIAL PARALYSIS
The occurrence of mast cells is studied in the normal facial nerve and in the facial nerve post mortem exam of patients with chronic suppurative otitis media without associated facial paralysis. A small number of mast cells were found in the normal facial nerve. These cells were usually located in close proximity to the endoneural and epineural blood vessels. The number of mast cells was i...
متن کاملProtein Profiling of the Secretome of FcεRI Activated RBL-2H3.1 Cells
Background: Secretory proteins of IgE receptor activated mast cells and basophils play a pivotal role in the generation of immediate and long term immune responses in allergy and type I hypersensitivity. Objective: The present study aims to generate a 2-D map and profile of proteins secreted from a high secretory variant of the rat basophilic leukemia cell line, RBL-2H3.1, which in view of the ...
متن کاملMast Cell Leukemia with Ascites and Multiple Organs Damage
Mast Cell Leukemia (MCL), a rare subtype of systemic mastocytosis is defined by bone marrow involvement as atypical and aleukemic mast cells, if more than 20% and less than 10% of peripheral WBCs are mast cells, respectively. We met a case of aleukemic MCL presenting with anemia and ascites for 2 years, referred for BM evaluation, suspicious of leukemia. Our findings included BM involveme...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Clinical and diagnostic laboratory immunology
دوره 11 6 شماره
صفحات -
تاریخ انتشار 2004